Amazon North American Fulfillment
4,100 Employees

Southern Illinois University Edwardsville
3,500 Employees

Anderson Healthcare
1,600 Employees

U.S. Steel
1,200 Employees

Wieland Rolled Products (formerly Olin Brass)
1,118 Employees

Phillips 66 Wood River Refinery
1,100 Employees

Alton Memorial Hospital
1,017 Employees

Madison County Government
984 Employees

Gateway Regional Medical Center
955 Employees

Edwardsville CUSD #7
922 Employees

Alton CUSD #11
806 Employees

AFS Keystone
830 Employees

Basler Electric Company
800 Employees

Fairmount Park Inc.
800 Employees

GEODIS
750 Employees

OSF St. Anthony's Health Center
733 Employees

Granite City CUSD #9
650 Employees

Lewis and Clark Community College
641 Employees

Amsted Rail
637 Employees

GRP Wegman
565 Employees

Triad CUSD #2
543 Employees

West Star Aviation
540 Employees

Alton Square
500 Employees

Glik Stores
500 Employees

Buesey Bank
400 Employees

YMCA of Edwardsville
400 Employees

Walmart of Glen Carbon
340 Employees

Madison County Transit
265 Employees

Meridian Village Senior Living Community
200 Employees

Eden Village Retirement Community
180 Employees

Lowe's Home Improvement
150 Employees

Sourced from Leadership Council Southwestern Illinois, business self-reporting, and online resources.